Fetal endocrine axes mRNA expression levels are related to sex and intrauterine position
This study suggests that there are sexually different mechanisms to regulate the HPA and HPG axes during fetal development. Higher mRNA expression levels of endocrine axes components may be a mechanism to help females cope with prolonged androgen exposure over a long gestational period. Additionally, these findings suggest different coordination requirements of male and female endocrine axes during stages of fetal development.
Authors
- Ruth Fishman (ORCID: https://orcid.org/0000-0001-5769-3459)
- Yoni Vortman (ORCID: https://orcid.org/0000-0003-1779-7880)
- Lee Koren (ORCID: https://orcid.org/0000-0002-7425-501X)
- Devorah Matas
- Tirza Doniger (ORCID: https://orcid.org/0000-0001-6708-8404)
- Ariel Yael
Institutions
- Bar-Ilan University (IL)
- Weizmann Institute of Science (IL)
- Tel Hai Academic College (IL)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1186/s13293-024-00637-9
- Citations
- 1
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.64
Funders
- University of Calgary
- Israel Science Foundation