RING finger protein 5 protects against acute myocardial infarction by inhibiting ASK1
We demonstrated the protective effect of RNF5 on myocardial infarction and its function was dependent on inhibiting the activation of ASK1, which adds a new regulatory component to the myocardial infarction associated network and promises to enable new therapeutic strategy.
Authors
- Hong Wan (ORCID: https://orcid.org/0000-0002-1119-2955)
- Guanglin Wang (ORCID: https://orcid.org/0000-0002-6269-5704)
- Zhen Liu (ORCID: https://orcid.org/0009-0007-9034-2969)
- Bizhen Dong (ORCID: https://orcid.org/0009-0001-7448-0313)
- Jianqing Zhang (ORCID: https://orcid.org/0000-0002-5822-2218)
- Zhangqian Tao
- Chihua Wang
Institutions
- Yangtze University (CN)
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Huanggang Central Hospital (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1186/s12872-024-04070-z
- Citations
- 5
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 1.17