Estimated Exposure to 6 Potentially Hepatotoxic Botanicals in US Adults

In this survey study, an estimated 15.6 million US adults consumed at least 1 botanical product with liver liability within the past 30 days, comparable with the number of people who consumed nonsteroidal anti-inflammatory drugs and a commonly prescribed hypolipidemic drug. Given a lack of regulatory oversight on the manufacturing and testing of botanical products, clinicians should be aware of possible adverse events from consumption of these largely unregulated products.

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Publication Details

Journal
JAMA Network Open
Published
2024-08-05
DOI
https://doi.org/10.1001/jamanetworkopen.2024.25822
Citations
20
Primary Topic
Natural Compound Pharmacology Studies
Type
article
Field-Weighted Citation Impact
11.99
Controls
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article

Estimated Exposure to 6 Potentially Hepatotoxic Botanicals in US Adults

Alisa Likhitsup, Vincent Chen, Robert J. Fontana
20 citations
JAMA Network Open
Natural Compound Pharmacology Studies
11.99
article

Estimated Exposure to 6 Potentially Hepatotoxic Botanicals in US Adults

Alisa Likhitsup, Vincent Chen, Robert J. Fontana
article en
20 citations

Abstract

In this survey study, an estimated 15.6 million US adults consumed at least 1 botanical product with liver liability within the past 30 days, comparable with the number of people who consumed nonsteroidal anti-inflammatory drugs and a commonly prescribed hypolipidemic drug. Given a lack of regulatory oversight on the manufacturing and testing of botanical products, clinicians should be aware of possible adverse events from consumption of these largely unregulated products.

JAMA Network OpenVol. 7(8)
University of Michigan (US)
Zero hunger
Openalex Percentile: Top 1%
Natural Compound Pharmacology Studies
11.99
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