Modernizing the Data Infrastructure for Clinical Research to Meet Evolving Demands for Evidence
We describe a vision for a modernized infrastructure that is centered around 2 related concepts. First, allowing the collection and rigorous evaluation of multiple data sources and types and, second, enabling the possibility to reuse health data for multiple purposes. We address the need for multidisciplinary collaboration and suggest ways to measure progress toward this goal.
Authors
- Grant D. Huang (ORCID: https://orcid.org/0000-0002-1217-0002)
- Walter J. Koroshetz (ORCID: https://orcid.org/0000-0001-7292-7831)
- Lee A. Fleisher (ORCID: https://orcid.org/0000-0003-2899-2294)
- Derek C. Angus (ORCID: https://orcid.org/0000-0002-7026-5181)
- Gregory Curfman (ORCID: https://orcid.org/0000-0002-9157-9585)
- Cynthia Grossman (ORCID: https://orcid.org/0000-0002-5849-6235)
- Nancy Kass (ORCID: https://orcid.org/0000-0003-3833-8456)
- Kaleab Z. Abebe (ORCID: https://orcid.org/0000-0002-3644-8419)
- Roy S. Herbst (ORCID: https://orcid.org/0000-0003-2535-5847)
- Deepak L. Bhatt (ORCID: https://orcid.org/0000-0002-1278-6245)
- Stacey J. Adam (ORCID: https://orcid.org/0000-0002-4590-5175)
- Adrian F. Hernandez (ORCID: https://orcid.org/0000-0003-3387-9616)
- Stephanie R. Morain (ORCID: https://orcid.org/0000-0001-7278-7517)
- Rachel Bender Ignacio (ORCID: https://orcid.org/0000-0001-6167-1447)
- Sharon A. Brangman (ORCID: https://orcid.org/0000-0002-0429-8655)
- Rohan Khera (ORCID: https://orcid.org/0000-0001-9467-6199)
- Bhakti K. Patel (ORCID: https://orcid.org/0000-0002-6517-2175)
- Scott M. Berry (ORCID: https://orcid.org/0000-0002-3541-0443)
- Ali B. Abbasi (ORCID: https://orcid.org/0000-0002-1039-2832)
- Peter James O'Dwyer (ORCID: https://orcid.org/0000-0002-9302-4073)
- Robert O. Bonow (ORCID: https://orcid.org/0000-0003-2277-3605)
- Diane Holder
- Tufia C. Haddad (ORCID: https://orcid.org/0000-0001-8226-3581)
- Joseph S. Ross (ORCID: https://orcid.org/0000-0002-9218-3320)
- Anne C. Chiang (ORCID: https://orcid.org/0000-0002-2111-4694)
- Atul J. Butte (ORCID: https://orcid.org/0000-0002-7433-2740)
- Sheila A. Prindiville (ORCID: https://orcid.org/0000-0003-1118-9761)
- Steven R. Cummings (ORCID: https://orcid.org/0000-0001-8808-260X)
- Caroline Marra (ORCID: https://orcid.org/0000-0003-0835-7875)
- Preeti Malani (ORCID: https://orcid.org/0000-0002-8263-8408)
- Stephen James Nicholls (ORCID: https://orcid.org/0000-0002-9668-4368)
- Anne Rentoumis Cappola (ORCID: https://orcid.org/0000-0002-0883-9754)
- Christopher Seymour (ORCID: https://orcid.org/0000-0001-8330-8489)
- Roger Lewis (ORCID: https://orcid.org/0000-0002-0020-4869)
- Robert M. Califf (ORCID: https://orcid.org/0000-0003-0231-3724)
- Susan A. Murphy (ORCID: https://orcid.org/0000-0002-2032-4286)
- Joanne Waldstreicher (ORCID: https://orcid.org/0000-0002-3992-4636)
- Laura J. Esserman (ORCID: https://orcid.org/0000-0001-9202-4568)
- Tracy A. Lieu (ORCID: https://orcid.org/0000-0002-3516-4617)
- Amy P. Abernethy (ORCID: https://orcid.org/0000-0001-6930-8722)
- Martin Landray (ORCID: https://orcid.org/0000-0001-6646-827X)
- Mary Mcdermott (ORCID: https://orcid.org/0000-0002-3724-7619)
- Kathy Rowan (ORCID: https://orcid.org/0000-0001-8217-5602)
- Marion Campbell (ORCID: https://orcid.org/0000-0001-5386-4097)
- Stuart G. Nicholls (ORCID: https://orcid.org/0000-0003-0485-9069)
- Kirsten Bibbins‐Domingo (ORCID: https://orcid.org/0000-0002-8962-0622)
- John S. Brownstein (ORCID: https://orcid.org/0000-0001-8568-5317)
- Harlan M. Krumholz (ORCID: https://orcid.org/0000-0003-2046-127X)
- Christa Lese Martin (ORCID: https://orcid.org/0000-0002-8071-5780)
- Jamy D. Ard (ORCID: https://orcid.org/0000-0002-1643-6795)
- Alison Huang
- Leora Horn
- Michael Berkwits (ORCID: https://orcid.org/0009-0005-1316-5861)
- Ralph Gonzalez
- Mark McClellan
- Gordon D. Rubenfeld
- Joseph B. Franklin
- Eric D. Peterson
- Marc Bonten
- Tracy Y. Wang
- Melinda Buntin (ORCID: https://orcid.org/0000-0002-5511-9805)
- Rod Stephen Taylor (ORCID: https://orcid.org/0000-0002-6538-5760)
Institutions
- Biogen (United States) (US)
- Johns Hopkins University (US)
- University of Pittsburgh (US)
- University of California, San Francisco (US)
- University of California System (US)
- Yale University (US)
- Highland Community College - Illinois (US)
- Intensive Care National Audit & Research Centre (GB)
- University of Pennsylvania (US)
- McMaster University (CA)
Publication Details
- Journal
- JAMA
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1001/jama.2024.0268
- Citations
- 22
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 10.15