Chidamide induces cell cycle arrest via NR4A3/P21 axis upregulation to suppress relapsed and refractory acute myeloid leukemia
We have discovered a novel epigenetic regulatory mechanism of chidamide in the treatment of relapsed and refractory acute myeloid leukemia (R/R AML).
Authors
- Jianmin Luo
- Yifan Gao (ORCID: https://orcid.org/0000-0002-9184-0085)
- Jiazi Zhou
- Feng Zhu (ORCID: https://orcid.org/0000-0001-6030-9251)
- Shuyu Wang (ORCID: https://orcid.org/0000-0003-3648-8071)
- Fuyi Luo
- Xuefeng Feng
Institutions
- Hebei Medical University (CN)
- Hebei North University (CN)
- Soochow University (CN)
- Second Hospital of Hebei Medical University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Biochemical and Biophysical Research Communications
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1016/j.bbrc.2024.150493
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.45