1,3-Difunctionalization of Alkenes by Cobaloxime Photocatalysis
Represented herein is the first 1,3-difunctionalization of alkenes via photocatalysis. A single cobaloxime is used to carry out two catalytic cycles in which cobaloxime is used not only as a photocatalyst to initiate the reaction but also as a metal catalyst for the β-H elimination process. Electron-deficient alkenes, electron-rich alkenes, and unactivated alkenes could be directly converted to 1,3-bisphosphorylated products, even unsymmetric 1,3-bisphosphorylated products, with only H<sub>2</sub> as a byproduct under extremely mild reaction conditions.
Authors
- Chen‐Ho Tung (ORCID: https://orcid.org/0000-0001-9999-9755)
- Jixin Yu
- Yuanyuan Cheng (ORCID: https://orcid.org/0000-0002-4749-3389)
- Li‐Zhu Wu (ORCID: https://orcid.org/0000-0002-5561-9922)
- Bin Chen (ORCID: https://orcid.org/0000-0003-0437-1442)
- Xin-Yi Zeng
Institutions
- Chinese Academy of Sciences (CN)
- Technical Institute of Physics and Chemistry (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1021/acs.orglett.4c02027
- Citations
- 9
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- National Key Research and Development Program of China