A Formal Synthesis of (+)-Hannokinol Using a Chiral Horner–Wittig Reagent

Herein, we report a concise and efficient formal synthesis of (+)-hannokinol. Key to this new strategy is the use of a chiral Horner-Wittig reagent, readily available from 2-deoxy-D-ribose, to introduce the chiral 1,3-diol motif.

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Publication Details

Journal
Molecules
Published
2024-08-05
DOI
https://doi.org/10.3390/molecules29153710
Citations
1
Primary Topic
Phytochemical compounds biological activities
Type
article
Field-Weighted Citation Impact
0.23
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A Formal Synthesis of (+)-Hannokinol Using a Chiral Horner–Wittig Reagent

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Molecules
Phytochemical compounds biological activities
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article

A Formal Synthesis of (+)-Hannokinol Using a Chiral Horner–Wittig Reagent

Fabia Mittendorf, Michael Tapera, Adrián Gómez‐Suárez, Stefan F. Kirsch, Ibrahim-Ethem Celik, Federica Borghi, Jan Lukas Mayer-Figge
article en
1 citations

Abstract

Herein, we report a concise and efficient formal synthesis of (+)-hannokinol. Key to this new strategy is the use of a chiral Horner-Wittig reagent, readily available from 2-deoxy-D-ribose, to introduce the chiral 1,3-diol motif.

MoleculesVol. 29(15)
University of Wuppertal (DE)
Openalex Percentile: Top 43%
Phytochemical compounds biological activities
0.23
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