The roles played by hsa-miR-223-5p and mutations in the <i>S</i> gene of SARS-CoV-2 in COVID-19

Increased hsa-miR-223-5p may be a main cause for the downregulation of IL-2Rα, which is a main developer of T-regulatory lymphocytes. The mutations in the S gene of SARS-CoV-2-infected patients may affect immune responses to the molecule and alter the avidity of virus-human cell interactions.

Authors

Ashraf Kariminik (ORCID: https://orcid.org/0000-0001-6489-9500)
Maryam Ghane (ORCID: https://orcid.org/0000-0003-0305-0241)
Zeyad Sadeg Sabbar

Institutions

Islamic Azad University, Science and Research Branch (IR)
Islamic Azad University Kerman (IR)
Islamic Azad University Islamshahr Branch (IR)

Publication Details

Journal: Laboratory Medicine
Published: 2024-08-05
DOI: https://doi.org/10.1093/labmed/lmae066
Citations: 2
Primary Topic: SARS-CoV-2 and COVID-19 Research
Type: article
Field-Weighted Citation Impact: 0.78

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article

The roles played by hsa-miR-223-5p and mutations in the S gene of SARS-CoV-2 in COVID-19

Ashraf Kariminik, Maryam Ghane, Zeyad Sadeg Sabbar

Aug 5, 2024

2 citations

Laboratory Medicine

SARS-CoV-2 and COVID-19 Research

0.78

article

The roles played by hsa-miR-223-5p and mutations in the S gene of SARS-CoV-2 in COVID-19

Ashraf Kariminik, Maryam Ghane, Zeyad Sadeg Sabbar

August 5, 2024article en

2 citations

Abstract

Increased hsa-miR-223-5p may be a main cause for the downregulation of IL-2Rα, which is a main developer of T-regulatory lymphocytes. The mutations in the S gene of SARS-CoV-2-infected patients may affect immune responses to the molecule and alter the avidity of virus-human cell interactions.

Laboratory MedicineVol. 56(1)

Islamic Azad University, Science and Research Branch (IR), Islamic Azad University Kerman (IR), Islamic Azad University Islamshahr Branch (IR)

Good health and well-being

Openalex Percentile: Top 28%

SARS-CoV-2 and COVID-19 Research

0.78

DOI Source OpenAlex

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