The potential effect of romosozumab on perioperative management for instrumentation surgery
Romosozumab significantly increased the regional vBMD as well as biomechanical parameters, potentially offering clinical benefits in reducing post-operative complications in patients with osteoporosis undergoing orthopedic instrumentation surgery. This study highlights the novel advantages of romosozumab treatment and advocates further research on its effectiveness in perioperative management.
Authors
- Toshiyuki Shirahata
- Ryo Yamamura
- Soji Tani
- Yusuke Oshita (ORCID: https://orcid.org/0000-0003-1908-2803)
- Tomoaki Toyone (ORCID: https://orcid.org/0000-0001-7918-2131)
- Katsunori Inagaki (ORCID: https://orcid.org/0000-0002-2987-9894)
- Koki Tsuchiya (ORCID: https://orcid.org/0009-0002-2530-1996)
- Takashi Nagai (ORCID: https://orcid.org/0000-0002-8815-1182)
- Koji Ishikawa (ORCID: https://orcid.org/0000-0003-3689-5662)
- Kudo Yoshifumi
- Tomoko Towatari
- Kazuki Wada (ORCID: https://orcid.org/0009-0001-0560-8424)
Institutions
- SHOWA Medical University (JP)
- SHOWA Medical University Northern Yokohama Hospital (JP)
- Koto Hospital (JP)
- Duke University Hospital (US)
- SHOWA Medical University Koto Toyosu Hospital (JP)
Publication Details
- Journal
- JOR Spine
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1002/jsp2.1356
- Citations
- 13
- Primary Topic
- Orthopaedic implants and arthroplasty
- Type
- article
- Field-Weighted Citation Impact
- 7.45
Funders
- Japan Society for the Promotion of Science