Toll-Like Receptor 7-Expressed Macrophages Are Involved in the Pathogenesis of Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction
TLR7-expressing macrophages are involved in the innate immune response underlying esophageal achalasia and EGJOO. This result will lead to the elucidation of new pathogenetic mechanisms and the development of novel therapeutic targets.
Authors
- Tadashi Yoshizawa (ORCID: https://orcid.org/0000-0001-8136-3281)
- Kenichi Hakamada (ORCID: https://orcid.org/0000-0001-6513-1202)
- Tatsuya Mikami (ORCID: https://orcid.org/0000-0002-6657-6446)
- Daisuke Chinda (ORCID: https://orcid.org/0000-0003-1690-5923)
- Hidezumi Kikuchi (ORCID: https://orcid.org/0000-0002-5163-9563)
- Yohei Sawada
- Tetsuyuki Tateda
- Hiroto Hiraga (ORCID: https://orcid.org/0000-0002-6874-4415)
- Shinsaku Fukuda (ORCID: https://orcid.org/0000-0002-4788-1816)
- Shogo Kawaguchi (ORCID: https://orcid.org/0000-0001-5599-1110)
- Shukuko Yoshida (ORCID: https://orcid.org/0000-0002-3197-8664)
- Takahiro Muroya (ORCID: https://orcid.org/0009-0004-5873-2973)
- Shinji Ota
- Keisuke Hasui (ORCID: https://orcid.org/0000-0003-2637-0571)
- Shiro Hayamizu
- Hirotake Sakuraba (ORCID: https://orcid.org/0000-0002-6075-1282)
- Tetsuya Tatsuta (ORCID: https://orcid.org/0000-0003-0228-8063)
- Masatoshi Kaizuka
- Hiroshi Kijima (ORCID: https://orcid.org/0000-0002-2366-9896)
Institutions
- Hirosaki University (JP)
- Hirosaki University Hospital (JP)
Publication Details
- Journal
- Digestion
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1159/000540693
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00