Uncovering the role of RPL8 in glutathione synthesis-dependent ferroptosis control in hepatocellular carcinoma
<i>RPL8</i> plays a key role in regulating HCC ferroptosis and tumor progression, affecting cellular defense by regulating GSH synthesis. These insights highlight <i>RPL8</i> as a promising target for therapeutic intervention in HCC.
Authors
- Dong Jiang (ORCID: https://orcid.org/0000-0003-4380-7683)
- Ye Tao (ORCID: https://orcid.org/0000-0001-5862-9520)
- Yiran Li (ORCID: https://orcid.org/0000-0002-4658-3876)
- Hao Zhang (ORCID: https://orcid.org/0000-0002-0049-1220)
- Jing Luo (ORCID: https://orcid.org/0009-0008-3540-4191)
Institutions
- Fudan University (CN)
- Zhongshan Hospital (CN)
Publication Details
- Journal
- Archives of Medical Science
- Published
- 2024-08-05
- DOI
- https://doi.org/10.5114/aoms/191789
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00