Necrotic Change of Tunica Media Plays a Key Role in the Development of Coronary Artery Lesions in Kawasaki Disease
There is potential involvement of edematous dissociation of the tunica media in the development of KD vasculitis. Furthermore, the distinctive anti-inflammatory effects of the anti-IL-33/ST2 axis drugs suggest novel therapeutic options for patients with refractory KD.
Authors
- Hiroki Yasudo (ORCID: https://orcid.org/0000-0002-8768-8746)
- Shunji Hasegawa (ORCID: https://orcid.org/0000-0002-1438-7993)
- Reiji Fukano (ORCID: https://orcid.org/0000-0002-4087-3426)
- Takako Waniishi
- Masaya Sugiyama (ORCID: https://orcid.org/0000-0002-9084-7197)
- Yuji Ohnishi (ORCID: https://orcid.org/0000-0001-7109-476X)
- Takahiro Motonaga
- Seigo Okada (ORCID: https://orcid.org/0000-0001-9347-2522)
- Aiko Sakai
Institutions
- Yamaguchi University (JP)
- Kyorin University (JP)
- National Center for Global Health and Medicine (JP)
- Center for Global Health (US)
Publication Details
- Journal
- Circulation Journal
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1253/circj.cj-24-0295
- Citations
- 5
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Japan Agency for Medical Research and Development
- Japan Blood Products Organization
- Japan Society for the Promotion of Science