Combination of Metformin and Epigallocatechin-3-Gallate Lowers Cortisol, 11β-Hydroxysteroid Dehydrogenase Type 1, and Blood Glucose Levels in Sprague Dawley Rats with Obesity and Diabetes
Combining EGCG with metformin exhibited synergistic effects compared with monotherapy for managing diabetes, leading to improved outcomes in reduction of baseline cortisol levels along with reduction in 11β-HSD1 and blood glucose levels.
Authors
- Nyoman Suci Widyastiti (ORCID: https://orcid.org/0000-0002-4083-1293)
- Muflihatul Muniroh
- Neni Susilaningsih (ORCID: https://orcid.org/0000-0003-1960-507X)
- Nani Maharani (ORCID: https://orcid.org/0000-0001-5984-6439)
- Diana Mazaya Atsarina
Institutions
- Diponegoro University (ID)
Publication Details
- Journal
- Journal of Obesity & Metabolic Syndrome
- Published
- 2024-08-05
- DOI
- https://doi.org/10.7570/jomes23080
- Citations
- 3
- Primary Topic
- Tea Polyphenols and Effects
- Type
- article
- Field-Weighted Citation Impact
- 1.27