Accelerated Fibrosis Progression of Diabetic Nephropathy From High Uric Acid's Activation of the ROS/NLRP3/SHP2 Pathway in Renal Tubular Epithelial Cells Under High Glucose Conditions.
In a high-glucose environment, high uric acid can promote the fibrotic progression of diabetic nephropathy by activating the ROS/NLRP3/SHP2 pathway, leading to mesenchymal transition between renal tubular epithelial cells.
Authors
- Qin Yu (ORCID: https://orcid.org/0000-0001-6379-9444)
- Jiwei Zhang (ORCID: https://orcid.org/0000-0001-8912-5069)
- Li Zhang (ORCID: https://orcid.org/0000-0002-9386-8938)
- Ling Tian
Publication Details
- Journal
- PubMed
- Published
- 2025-09-01
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06