Correlation of NAT10 expression with clinical data and survival profiles in esophageal squamous cell carcinoma patients, and its impact on cell proliferation and apoptosis.
The observed overexpression of NAT10 in ESCC tissues is associated with larger tumor diameters and reduced patient survival. NAT10 appears to play a pivotal role in the progression of esophageal cancer by influencing cell proliferation and apoptosis. These findings suggest potential clinical implications, with Ki67 and Caspase3 potentially participating in this intricate molecular biological process.
Authors
- Yongling Ji
- Jin Wang (ORCID: https://orcid.org/0000-0002-0062-2489)
- Xiaoyan Zhang (ORCID: https://orcid.org/0000-0002-0646-4418)
- Xinyi Wang (ORCID: https://orcid.org/0009-0002-6349-8013)
- Wei Sun (ORCID: https://orcid.org/0000-0003-0260-4484)
- Xiaoying Shen (ORCID: https://orcid.org/0000-0002-0618-0423)
Institutions
- Chinese Academy of Sciences (CN)
- Zhejiang Cancer Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-01
- DOI
- https://doi.org/10.14670/hh-18-752
- Citations
- 3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.70