Relationship of CYP3A4*1B Single Nucleotide Polymorphism to the Efficiency and Safety Profiles of Haloperidol in Patients Enduring Acute Alcoholic Hallucinosis

The study demonstrated that the <i>392A</i> > <i>G</i> polymorphism of the <i>CYP3A4</i>*<i>1B</i> gene <i>(rs2740574)</i> in patients with acute alcoholic hallucinosis does not affect the efficacy and safety rates of haloperidol therapy.

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Publication Details

Journal
Psychopharmacology Bulletin
Published
2025-08-12
DOI
https://doi.org/10.64719/pb.4471
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
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article

Relationship of CYP3A4*1B Single Nucleotide Polymorphism to the Efficiency and Safety Profiles of Haloperidol in Patients Enduring Acute Alcoholic Hallucinosis

I A Zaytsev, К. А. Акмалова, А. Е. Петухов, П. О. Бочков et al.
Psychopharmacology Bulletin
Pharmacogenetics and Drug Metabolism
article

Relationship of CYP3A4*1B Single Nucleotide Polymorphism to the Efficiency and Safety Profiles of Haloperidol in Patients Enduring Acute Alcoholic Hallucinosis

I A Zaytsev, К. А. Акмалова, А. Е. Петухов, П. О. Бочков, Evgeny Bryun, Aleksandra Aleksandrovna Parkhomenko, Irina V. Bure, V A Ivanchenko, S A Pozdniakov, Valentin Yurievich Skryabin, Dmitry Alekseevich Sychev, Михаил Сергеевич Застрожин, Smirnov Vv
article en

Abstract

The study demonstrated that the <i>392A</i> > <i>G</i> polymorphism of the <i>CYP3A4</i>*<i>1B</i> gene <i>(rs2740574)</i> in patients with acute alcoholic hallucinosis does not affect the efficacy and safety rates of haloperidol therapy.

Psychopharmacology BulletinVol. 53(4)
California Department of Toxic Substances Control (US), American Society of Addiction Medicine (US), Moscow Clinical Scientific Center (RU), Russian Medical Academy of Continuous Professional Education (RU), National Drug Addiction Center (BG), Institute of Plant Genetics, Polish Academy of Sciences (PL), Research Center of Neurology (RU), Institute of Predictive and Personalized Medicine of Cancer (ES), Federal Medical-Biological Agency (RU)
Good health and well-being
Openalex Percentile: Top 100%
Pharmacogenetics and Drug Metabolism
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Relationship of CYP3A4*1B Single Nucleotide Polymorphism to the Efficiency and Safety Profiles of Haloperidol in Patients Enduring Acute Alcoholic Hallucinosis — I A Zaytsev, К. А. Акмалова, et al. · Psychopharmacology Bulletin (2025) | TGRS Research Map | TGRS