DeepRetNet: retinal disease classification using attention UNet++ based segmentation and optimized deep learning technique

Abstract Human eyesight depends significantly on retinal tissue. The loss of eyesight may result from infections of the retinal tissue that are treated slowly or not at all. Furthermore, when a large dataset is involved, the diagnosis is susceptible to inaccuracies. Hence, a fully automated approach based on deep learning for diagnosing retinal illness is proposed in order to minimise human intervention while maintaining high precision in classification. The proposed Attention UNet++ based Deep Retinal Network (Attn_UNet++ based DeepRetNet) is designed for classifying the retinal disease along with the segmentation criteria. In this, the Attn_UNet++ is employed for segmentation, wherein the UNet++ with dense connection is hybridized with Attention module for enhancing the segmentation accuracy. Then, the disease classification is performed using the DeepRetNet, wherein the loss function optimization is employed using the Improved Gazelle optimization (ImGaO) algorithm. Here, the adaptive weighting strategy is added with the conventional Gazelle algorithm for enhancing the global search with fast convergence rate. The performance analysis of proposed Attn_UNet++ based DeepRetNet based on Accuracy, Specificity, Precision, Recall, F1-Measure, and MSE accomplished the values of 97.20%, 98.36%, 95.90%, 95.50%, 96.53%, and 2.80% respectively.

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Publication Details

Journal
Journal of Combinatorial Optimization
Published
2026-11-11
DOI
https://doi.org/10.1007/s10878-026-01493-6
Citations
2
Primary Topic
Retinal Imaging and Analysis
Type
article
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article

DeepRetNet: retinal disease classification using attention UNet++ based segmentation and optimized deep learning technique

R. R. Prianka, R. Porselvi, W Nancy, Arun Raghesh J T
2 citations
Journal of Combinatorial Optimization
Retinal Imaging and Analysis
article

DeepRetNet: retinal disease classification using attention UNet++ based segmentation and optimized deep learning technique

R. R. Prianka, R. Porselvi, W Nancy, Arun Raghesh J T
article en
2 citations

Abstract

Abstract Human eyesight depends significantly on retinal tissue. The loss of eyesight may result from infections of the retinal tissue that are treated slowly or not at all. Furthermore, when a large dataset is involved, the diagnosis is susceptible to inaccuracies. Hence, a fully automated approach based on deep learning for diagnosing retinal illness is proposed in order to minimise human intervention while maintaining high precision in classification. The proposed Attention UNet++ based Deep Retinal Network (Attn_UNet++ based DeepRetNet) is designed for classifying the retinal disease along with the segmentation criteria. In this, the Attn_UNet++ is employed for segmentation, wherein the UNet++ with dense connection is hybridized with Attention module for enhancing the segmentation accuracy. Then, the disease classification is performed using the DeepRetNet, wherein the loss function optimization is employed using the Improved Gazelle optimization (ImGaO) algorithm. Here, the adaptive weighting strategy is added with the conventional Gazelle algorithm for enhancing the global search with fast convergence rate. The performance analysis of proposed Attn_UNet++ based DeepRetNet based on Accuracy, Specificity, Precision, Recall, F1-Measure, and MSE accomplished the values of 97.20%, 98.36%, 95.90%, 95.50%, 96.53%, and 2.80% respectively.

Journal of Combinatorial OptimizationVol. 52(5)
New Horizon College of Engineering (IN), Jeppiaar Institute of Technology (IN)
Good health and well-being
Retinal Imaging and Analysis
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DeepRetNet: retinal disease classification using attention UNet++ based segmentation and optimized deep learning technique — R. R. Prianka, R. Porselvi, et al. · Journal of Combinatorial Optimization (2026) | TGRS Research Map | TGRS