Association of CYP2D6*4 Polymorphism with the Steady- State Concentration of Haloperidol in Patients with Alcohol-Induced Psychotic Disorders
It can be concluded that patients with the <i>GA</i> genotype have a higher risk of ADRs compared to patients who carry the <i>GG</i> genotype. It was shown that <i>CYP2D6*4</i> genetic polymorphism has a statistically significant effect on the steady-state concentration of haloperidol.
Authors
- I A Zaytsev
- К. А. Акмалова (ORCID: https://orcid.org/0000-0003-3505-8520)
- Н. П. Денисенко (ORCID: https://orcid.org/0000-0003-3278-5941)
- Evgeny Bryun (ORCID: https://orcid.org/0000-0002-9329-1155)
- V A Ivanchenko
- V V Noskov
- Valentin Yurievich Skryabin (ORCID: https://orcid.org/0000-0002-4942-8556)
- Dmitry Alekseevich Sychev (ORCID: https://orcid.org/0000-0002-4496-3680)
- Михаил Сергеевич Застрожин (ORCID: https://orcid.org/0000-0002-3964-9726)
- A A Parkhomenko (ORCID: https://orcid.org/0000-0002-3332-1033)
- S. A. Pozdnyakov (ORCID: https://orcid.org/0000-0002-5198-6637)
Institutions
- Poznań University of Economics and Business (PL)
- Moscow Clinical Scientific Center (RU)
- Russian Medical Academy of Continuous Professional Education (RU)
- National Drug Addiction Center (BG)
- Molecular Medicine Research Institute (US)
- Addiction Research Foundation (US)
- Research Center of Neurology (RU)
- Institute of Predictive and Personalized Medicine of Cancer (ES)
Publication Details
- Journal
- Psychopharmacology Bulletin
- Published
- 2025-08-12
- DOI
- https://doi.org/10.64719/pb.4450
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00