Lidocaine Ineffectiveness Suggests New Psychopharmacology Drug Target
These results suggest the possibility of the biological understanding of the combination of ADHD and PMS that is characteristic of the psychiatric disorder Premenstrual Dysphoric Disorder (PMDD). These results and comparison to family pedigrees of a neuromuscular channelopathy with overlapping symptoms suggest the possibility that the clinical phenotype in PMDD is produced by sensory overstimulation, and amenable to molecular understanding and treatment.
Authors
- Michael M. Segal (ORCID: https://orcid.org/0000-0002-2487-6221)
- Jonathan Diaz (ORCID: https://orcid.org/0000-0002-5064-3878)
- Irene Axelrod
- Joseph G. Gleeson (ORCID: https://orcid.org/0000-0002-0889-9220)
- Irina Mezhebovsky
- David Zurakowski (ORCID: https://orcid.org/0000-0003-3610-6942)
- Helen Chow (ORCID: https://orcid.org/0000-0002-1387-4693)
- Pnina Mintz
- Lynn Feldman
- Mark Mintz (ORCID: https://orcid.org/0000-0002-1738-9644)
- Mana Saraghi (ORCID: https://orcid.org/0000-0001-9742-9951)
- Chang Liu (ORCID: https://orcid.org/0000-0002-8723-7363)
- Victor Badner (ORCID: https://orcid.org/0000-0002-1210-9359)
- Cathy Devitt Smith
Institutions
- Boston Children's Hospital (US)
- Jacobi Medical Center (US)
- Smith Family (AU)
- AIDS Clinical Trials Group (US)
- University of California San Diego (US)
- Goldman Sachs (United States) (US)
- Office of Minority Health (US)
- Public Health Dayton & Montgomery County (US)
- Primary HealthCare (MT)
Publication Details
- Journal
- Psychopharmacology Bulletin
- Published
- 2025-08-12
- DOI
- https://doi.org/10.64719/pb.4441
- Citations
- 1
- Primary Topic
- Menstrual Health and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.88