Protein Biomarkers in Monocytes and CD4+ Lymphocytes for Predicting Lithium Treatment Response of Bipolar Disorder: a Feasibility Study with Tyramine-Based Signal- Amplified Flow Cytometry
CellPrint™ flow cytometry was able to detect differences in multiple proteins in monocytes and CD4<sup>+</sup> lymphocytes between lithium responders and non-responders. A large study is warranted to confirm or refute these findings.
Authors
- Nicholas M. Kaye (ORCID: https://orcid.org/0000-0002-2933-8908)
- Stephen J. Ganocy (ORCID: https://orcid.org/0000-0002-0801-3151)
- Mehmet Koyutürk (ORCID: https://orcid.org/0000-0002-3434-5512)
- Joseph R. Calabrese (ORCID: https://orcid.org/0000-0003-4647-8571)
- Hillard Michael Lazarus (ORCID: https://orcid.org/0000-0002-1159-5607)
- Marzieh Ayati (ORCID: https://orcid.org/0000-0002-5280-5738)
- David R. Kaplan (ORCID: https://orcid.org/0000-0002-7069-9254)
- Keming Gao (ORCID: https://orcid.org/0000-0003-1130-2461)
- Eric Christian
Institutions
- University Hospitals of Cleveland (US)
Publication Details
- Journal
- Psychopharmacology Bulletin
- Published
- 2025-08-12
- DOI
- https://doi.org/10.64719/pb.4424
- Citations
- 16
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 7.36