MDMA to Treat PTSD in Adults

Post-traumatic stress disorder (PTSD) has become one of the most common psychiatric diagnosis in the United States specifically within the veteran population. The current treatment options for this debilitating diagnosis include trauma-focused psychotherapies along with selective serotonin reuptake inhibitors (SSRI) and serotonin-norepinephrine reuptake inhibitors (SNRI).<sup>1</sup> MDMA has recently been shown as a novel therapeutic agent with promisingly results in the treatment of PTSD. MDMA is a psychoactive compound traditionally categorized as a psychedelic amphetamine that deemed a Schedule I controlled substance in the 1980s. Prior to its status as a controlled substance, it was used by psychotherapists for an array of psychiatric issues. In more recent times, MDMA has resurfaced as a potential therapy for PTSD and the data produced from randomized, controlled trials back the desire for MDMA to be utilized as an effective pharmacologic therapy in conjunction with psychotherapy.<sup>2</sup>.

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Publication Details

Journal
Psychopharmacology Bulletin
Published
2025-08-12
DOI
https://doi.org/10.64719/pb.4414
Citations
9
Primary Topic
Psychedelics and Drug Studies
Type
article
Field-Weighted Citation Impact
4.61
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article

MDMA to Treat PTSD in Adults

Elyse M. Cornett, Michael D Stocker, Omar Viswanath, Jackson Green et al.
9 citations
Psychopharmacology Bulletin
Psychedelics and Drug Studies
4.61
article

MDMA to Treat PTSD in Adults

Elyse M. Cornett, Michael D Stocker, Omar Viswanath, Jackson Green, Alan D. Kaye, Giustino Varrassi, Alaa A Abd-Elsayed, Kia Sayers, Dustin Latimer, Ivan Urits, Adam M. Kaye
article en
9 citations

Abstract

Post-traumatic stress disorder (PTSD) has become one of the most common psychiatric diagnosis in the United States specifically within the veteran population. The current treatment options for this debilitating diagnosis include trauma-focused psychotherapies along with selective serotonin reuptake inhibitors (SSRI) and serotonin-norepinephrine reuptake inhibitors (SNRI).<sup>1</sup> MDMA has recently been shown as a novel therapeutic agent with promisingly results in the treatment of PTSD. MDMA is a psychoactive compound traditionally categorized as a psychedelic amphetamine that deemed a Schedule I controlled substance in the 1980s. Prior to its status as a controlled substance, it was used by psychotherapists for an array of psychiatric issues. In more recent times, MDMA has resurfaced as a potential therapy for PTSD and the data produced from randomized, controlled trials back the desire for MDMA to be utilized as an effective pharmacologic therapy in conjunction with psychotherapy.<sup>2</sup>.

Psychopharmacology BulletinVol. 51(3)
Louisiana State University Health Sciences Center New Orleans (US)
Good health and well-being
Openalex Percentile: Top 9%
Psychedelics and Drug Studies
4.61
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