Impact of the Omics-Based Biomarkers on the Fluvoxamine’s Steady-State Concentration, Efficacy and Safety in Patients with Affective Disorders Comorbid with Alcohol Use Disorder
Thus, the effect of genetic polymorphism of the CYP3A4, CYP2C9, CYP2C9, CYP3A5, ABCB1, CYP2C19, CYP2C19, CYP2C19, SCL6A4, 5-HTR2A gene on the efficacy and safety profiles of fluvoxamine was not demonstrated in a group of 105 patients with depressive disorder and alcohol use disorder.
Authors
- А. К. Застрожина (ORCID: https://orcid.org/0000-0002-1622-6456)
- Elena Kaverina (ORCID: https://orcid.org/0000-0002-0264-8543)
- Е. А. Гришина (ORCID: https://orcid.org/0000-0002-5621-8266)
- M. S. Zastrozhin (ORCID: https://orcid.org/0000-0003-0607-4812)
- Dina Klepikov
- Evgeny Bryun (ORCID: https://orcid.org/0000-0002-9329-1155)
- Irina V. Bure (ORCID: https://orcid.org/0000-0003-2043-5848)
- VYu Smirnov
- Valentin Yurievich Skryabin (ORCID: https://orcid.org/0000-0002-4942-8556)
- Dmitry Alekseevich Sychev (ORCID: https://orcid.org/0000-0002-4496-3680)
- Kristina Ryzhikova
Institutions
- Peoples' Friendship University of Russia (RU)
- Sechenov University (RU)
- SKiN Health (CA)
- Russian Medical Academy of Continuous Professional Education (RU)
- Burn Institute (US)
- For farmers (United Kingdom) (GB)
- Addiction Research Foundation (US)
- Acıbadem Kadıköy Hospital (TR)
Publication Details
- Journal
- Psychopharmacology Bulletin
- Published
- 2025-08-12
- DOI
- https://doi.org/10.64719/pb.4393
- Citations
- 5
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 2.79