Epidural Space Cervical Spine: Review of Traumatic and Non-Traumatic Epidural Pathologies

The spinal epidural space located between the dura matter and the vertebral bodies can be affected by various pathologies. Understanding the radiological anatomy and clinical relevance of this space is of crucial importance for diagnostic and interventional therapeutic purposes. The cervical epidural space is particularly important due to its proximity to the cervical spinal cord and exiting nerve roots, where early detection of pathologies can prevent catastrophic neurological complications. In this concise review, we highlight the anatomy of the cervical epidural space and its boundaries and content as well as normal variants that mimic pathology on imaging. We discuss common etiologies that affect this space including traumatic and non-traumatic causes and their radiological appearance. Furthermore, the utility of computed tomography (CT) and magnetic resonance imaging (MRI) will be highlighted. Among the most common diseases affecting the cervical epidural space anteriorly is herniated discs and posteriorly facet degenerative changes. Infections and neoplastic processes integral to the cervical epidural space will be discussed in detail.