A Comprehensive Update of Lofexidine for the Management of Opioid Withdrawal Symptoms

Opiate addiction is increasing and plaguing the western world and specifically the U.S. It takes a large toll on both a personal and societal level and carries a high cost. Withdrawal is difficult, both related to withdrawal symptoms and renewed cravings. Lofexidine has been shown to be effective in reducing the former and could potentially aid in recovery and withdrawal.

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Publication Details

Journal
Psychopharmacology Bulletin
Published
2025-08-12
DOI
https://doi.org/10.64719/pb.4615
Citations
23
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
11.27
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article

A Comprehensive Update of Lofexidine for the Management of Opioid Withdrawal Symptoms

Celina G. Virgen, Omar Viswanath, Alan D. Kaye, Robbie Zusman et al.
23 citations
Psychopharmacology Bulletin
Opioid Use Disorder Treatment
11.27
article

A Comprehensive Update of Lofexidine for the Management of Opioid Withdrawal Symptoms

Celina G. Virgen, Omar Viswanath, Alan D. Kaye, Robbie Zusman, Jai Won Jung, Amnon A. Berger, Hisham Kassem, Ivan Urits, Jamal Hasoon, Anjana Patel, Mohammad Mousa
article en
23 citations

Abstract

Opiate addiction is increasing and plaguing the western world and specifically the U.S. It takes a large toll on both a personal and societal level and carries a high cost. Withdrawal is difficult, both related to withdrawal symptoms and renewed cravings. Lofexidine has been shown to be effective in reducing the former and could potentially aid in recovery and withdrawal.

Psychopharmacology BulletinVol. 50(3)
Georgetown University (US), Mount Sinai Medical Center (US)
Good health and well-being
Openalex Percentile: Top 2%
Opioid Use Disorder Treatment
11.27
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