Antiepileptic Drugs and Bone Health: Current Concepts

Chronic use of antiepileptic drugs (AEDs) can induce the development of adverse effects on bone metabolism. In epileptic patients treated with AED, the monitoring of biochemical markers of bone turnover, such as the measurement of serum 25 (OH) vitamin D, bone mineral density, before the beginning of the treatment and during the follow-up is not routinely required. In the future, monitoring of biochemical markers in epileptic patients treated with AED may help us for adequate prevention therapy.

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Publication Details

Journal
Psychopharmacology Bulletin
Published
2025-08-12
DOI
https://doi.org/10.64719/pb.4609
Citations
26
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
27.95
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article

Antiepileptic Drugs and Bone Health: Current Concepts

Erika Cione, Luca Gallelli, Antonio Siniscalchi, Leonardo Piro et al.
26 citations
Psychopharmacology Bulletin
Pharmacological Effects and Toxicity Studies
27.95
article

Antiepileptic Drugs and Bone Health: Current Concepts

Erika Cione, Luca Gallelli, Antonio Siniscalchi, Leonardo Piro, Giovambattista De Sarro, Séan Murphy
article en
26 citations

Abstract

Chronic use of antiepileptic drugs (AEDs) can induce the development of adverse effects on bone metabolism. In epileptic patients treated with AED, the monitoring of biochemical markers of bone turnover, such as the measurement of serum 25 (OH) vitamin D, bone mineral density, before the beginning of the treatment and during the follow-up is not routinely required. In the future, monitoring of biochemical markers in epileptic patients treated with AED may help us for adequate prevention therapy.

Psychopharmacology BulletinVol. 50(2)
Mater Misericordiae University Hospital (IE)
Good health and well-being
Openalex Percentile: Top 0%
Pharmacological Effects and Toxicity Studies
27.95
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