Coexistence of Lymphangioma Circumscriptum and Angiokeratoma in the Same Area: A Case Report

Lymphangioma is a rare benign malformation of lymphatic vessels. Lymphangioma Circumscriptum (LC) is the most common type. Angiokeratoma is a vascular lesion which is considered to be caused primarily by vascular ectasia in the papillary dermis and epidermal changes developing secondarily. Here we presented a 51-year-old patient developing angiokeratoma and LC in the same area with literature’s data. Previously, one case pointing out to the coexistence of LC and angiokeratoma in cutaneous tissue has been reported in the literature. In our case, the lesions’ general clinical appearance was consistent with angiokeratoma and dermoscopic examination revealed the findings of angiokeratoma in some areas, histopathologically one of the patients’ biopsies specimens revealed angiokeratoma, the other was consistent with lymphangioma. Coexistence of these two entities can lead to difficulty for diagnosis, histopathological examination is essential for differential diagnosis. Since the late onset of LC can be associated with localized obstructive lymphatic disorders, there is a necessity for the clinician to perform further investigations, establishing the diagnosis of LC has critical importance. Therefore our case points out that distinguishing between LC and angiokeratoma may be challenging for clinicians with only clinicodermoscopical findings, histopathological examination with advanced techniques is mandatory in making a differential diagnosis between these.