A Randomized, Placebo-Controlled Pilot Study of Quetiapine-XR Monotherapy or Adjunctive Therapy to Antidepressant in Acute Major Depressive Disorder with Current Generalized Anxiety Disorder
In this pilot study, quetiapine-XR was numerically superior to placebo in reducing depressive and anxiety symptoms in patients with MDD and current GAD. Large sample studies are warranted to support or refute these preliminary findings.
Authors
- Renrong Wu (ORCID: https://orcid.org/0000-0003-1758-4738)
- Carla Conroy (ORCID: https://orcid.org/0000-0002-7815-7353)
- Stephen J. Ganocy (ORCID: https://orcid.org/0000-0002-0801-3151)
- Joseph R. Calabrese (ORCID: https://orcid.org/0000-0003-4647-8571)
- Mary Beth Serrano
- David E. Kemp (ORCID: https://orcid.org/0000-0003-2653-5663)
- Philip K. Chan (ORCID: https://orcid.org/0000-0002-3878-4205)
- Keming Gao (ORCID: https://orcid.org/0000-0003-1130-2461)
- Jun Chen (ORCID: https://orcid.org/0000-0002-3837-2761)
- Ranran Li (ORCID: https://orcid.org/0000-0003-1723-9037)
- Ming Ren
Institutions
- University of Maryland, Baltimore (US)
- University of Maryland Medical Center (US)
Publication Details
- Journal
- Psychopharmacology Bulletin
- Published
- 2025-08-12
- DOI
- https://doi.org/10.64719/pb.4339
- Citations
- 10
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00