Agomelatine for Depression in Schizophrenia: A Case-Series

Our findings provide initial evidence that agomelatine is safe and efficacious in treating depressive symptoms in patients with schizophrenia. Furthermore, agomelatine seems to be effective for the treatment of negative symptoms. Randomized controlled trials are necessary to confirm these first observations.

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Publication Details

Journal
Psychopharmacology Bulletin
Published
2025-08-12
DOI
https://doi.org/10.64719/pb.4060
Citations
5
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Agomelatine for Depression in Schizophrenia: A Case-Series

H. Russmann, Jochen Mutschler, Nicolas Rüsch, Herdis Schönfelder et al.
5 citations
Psychopharmacology Bulletin
Schizophrenia research and treatment
article

Agomelatine for Depression in Schizophrenia: A Case-Series

H. Russmann, Jochen Mutschler, Nicolas Rüsch, Herdis Schönfelder, Wulf Rössler, Annette Beatrix Brühl, Uwe Herwig, Martin Grosshans
article en
5 citations

Abstract

Our findings provide initial evidence that agomelatine is safe and efficacious in treating depressive symptoms in patients with schizophrenia. Furthermore, agomelatine seems to be effective for the treatment of negative symptoms. Randomized controlled trials are necessary to confirm these first observations.

Psychopharmacology BulletinVol. 45(1)
University of Zurich (CH), Heidelberg University (DE), University Hospital Heidelberg (DE)
Good health and well-being
Openalex Percentile: Top 100%
Schizophrenia research and treatment
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