Lithium perchlorate as a new catalyst for efficient, mild and one-pot synthesis of 2,2-disubstituted imidazolidine derivatives from various aromatic ketones and ethylene diamine

A new strategy for the preparation of imidazolidine derivatives from reaction of different aromatic ketones with 1,2-ethane diamine in the presence of LiClO4 under the solution phase conditions is described. The products have been obtained in high to excellent yields and appropriate reaction times. The structure of resulting heterocycles has been determined by physical and spectroscopic data.