Synthesis, Characterization, and In vitro Anticancer Screening of Some Novel, Potential Acridone Analogues

The aim of present research work was to develop newer Acridone analogs exhibiting potential anticancer activity.The acridone analogues were synthesized by Ullmann condensation method & characterized by various spectral analysessuch as IR, NMR,Mass & Elemental analysis. Screening of title compounds for anticancer activity bysulphorhodamineB assay against MCF-7 cells & ADME studies of the compound showed encouraging results

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Publication Details

Journal
International Journal of Drug Design and Discovery
Published
2025-06-25
DOI
https://doi.org/10.37285/ijddd.3.2.6
Primary Topic
Cancer therapeutics and mechanisms
Type
article
Field-Weighted Citation Impact
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article

Synthesis, Characterization, and In vitro Anticancer Screening of Some Novel, Potential Acridone Analogues

International Journal of Drug Design and Discovery
Cancer therapeutics and mechanisms
article

Synthesis, Characterization, and In vitro Anticancer Screening of Some Novel, Potential Acridone Analogues

article en

Abstract

The aim of present research work was to develop newer Acridone analogs exhibiting potential anticancer activity.The acridone analogues were synthesized by Ullmann condensation method & characterized by various spectral analysessuch as IR, NMR,Mass & Elemental analysis. Screening of title compounds for anticancer activity bysulphorhodamineB assay against MCF-7 cells & ADME studies of the compound showed encouraging results

International Journal of Drug Design and DiscoveryVol. 3(2)
Bombay College of Pharmacy (IN)
Openalex Percentile: Top 100%
Cancer therapeutics and mechanisms
DOISourceOpenAlex
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Synthesis, Characterization, and In vitro Anticancer Screening of Some Novel, Potential Acridone Analogues · International Journal of Drug Design and Discovery (2025) | TGRS Research Map | TGRS