Latest Research in Genetic Associations and Epidemiology

28 research papers · 2026 median publication year

Top Research Topics in Genetic Associations and Epidemiology

Highest-Cited Papers

  1. Identification of immune cell mitochondrial dysfunction characteristics and clinical predictive biomarkers in sepsis via multi-cohort machine learning and single-cell RNA sequencing
  2. Causal association between allergic diseases and short stature: a mendelian randomization study revealing the potential mediating role of inflammatory proteins
  3. Cross-Cohort Integration of Blood DNA Methylation and Sepsis Transcriptomes Prioritizes TP53INP1 as a Candidate Associated with B-Cell Transcriptomic Patterns in Pediatric HAdV-7-Associated Sepsis
  4. Integrative Proteome-Wide Mendelian Randomization and Multi-Omics Analysis Identify ADM and CFH as Candidate Genes for Osteoarthritis
  5. Expression Analysis of Selected miRNAs in COVID-19 Patients
  6. Dynamic CD4+ T Cell Genetics Identifies Candidate Therapeutic Targets for Allergic Rhinitis: Mendelian Randomization with Exploratory Single-Cell Contextualization
  7. Limited evidence for causal effects of circulating inflammatory cytokines on the risk of selected hematologic malignancies: a two-sample Mendelian randomization study
  8. Unfixed HERV-K insertional polymorphisms as risk factors for multiple sclerosis in a Slavic cohort: the role of PTPRN2
  9. Discordant Interleukin-27 (IL-27) Subunit Transcription in Human Sepsis Exposes a Molecular-Attribution Gap
  10. Identification and validation of oxidative stress-related immune signatures in Hepatitis B Virus associated acute liver failure based on WGCNA and machine learning
  11. The way for early diagnosis of sepsis: Read host immune response via pan-infection transcriptomics and transfer learning
  12. Multimodal discovery of a pathogenic B cell-dependent T cell state in multiple sclerosis
  13. Interferon-driven gene signature identifies two distinct subgroups in rheumatoid factor-positive polyarticular juvenile idiopathic arthritis
  14. Optimizing efficacy to safety ratio of glucocorticoids in rheumatoid arthritis models by leveraging PPARα agonism
  15. The impact for causal associations between common diseases and inflammatory bowel disease: a disease-wide bidirectional Mendelian randomization study
  16. Immunomodulatory roles of the HLA family and B2M in atherosclerosis
  17. Mendelian randomization analysis of the causal relationship between allergic rhinitis and depression and underlying mediation mechanisms
  18. DNA hypo-methylation of the TNFΑ gene predicts response to methotrexate in rheumatoid arthritis but not in psoriatic arthritis
  19. Shared Genetic Basis of Autoimmune Diseases and Follicular Lymphoma by Mendelian Randomization and Multi-Omics
  20. TLPT Rheumatology for Clinicians: Pathogenetic Axes, Master‑Switch Nodes, Minimal and Transversal Attractors, and Bio‑Pharmacology
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L3 Region - - 2026 Sep Q3

Genetic Associations and Epidemiology

28 papers

Top Topics (10)

Genetic Associations and Epidemiology5
Rheumatoid Arthritis Research and Therapies3
Sepsis Diagnosis and Treatment2
Allergic Rhinitis and Sensitization2
Multiple Sclerosis Research Studies2
Asthma and respiratory diseases1
Virus-based gene therapy research1
MicroRNA in disease regulation1
Psoriasis: Treatment and Pathogenesis1
Ferroptosis and cancer prognosis1

Top Publications (20)

1.Identification of immune cell mitochondrial dysfunction characteristics and clinical predictive biomarkers in sepsis via multi-cohort machine learning and single-cell RNA sequencing2.Causal association between allergic diseases and short stature: a mendelian randomization study revealing the potential mediating role of inflammatory proteins3.Cross-Cohort Integration of Blood DNA Methylation and Sepsis Transcriptomes Prioritizes TP53INP1 as a Candidate Associated with B-Cell Transcriptomic Patterns in Pediatric HAdV-7-Associated Sepsis4.Integrative Proteome-Wide Mendelian Randomization and Multi-Omics Analysis Identify ADM and CFH as Candidate Genes for Osteoarthritis5.Expression Analysis of Selected miRNAs in COVID-19 Patients6.Dynamic CD4+ T Cell Genetics Identifies Candidate Therapeutic Targets for Allergic Rhinitis: Mendelian Randomization with Exploratory Single-Cell Contextualization7.Limited evidence for causal effects of circulating inflammatory cytokines on the risk of selected hematologic malignancies: a two-sample Mendelian randomization study8.Unfixed HERV-K insertional polymorphisms as risk factors for multiple sclerosis in a Slavic cohort: the role of PTPRN29.Discordant Interleukin-27 (IL-27) Subunit Transcription in Human Sepsis Exposes a Molecular-Attribution Gap10.Identification and validation of oxidative stress-related immune signatures in Hepatitis B Virus associated acute liver failure based on WGCNA and machine learning11.The way for early diagnosis of sepsis: Read host immune response via pan-infection transcriptomics and transfer learning12.Multimodal discovery of a pathogenic B cell-dependent T cell state in multiple sclerosis13.Interferon-driven gene signature identifies two distinct subgroups in rheumatoid factor-positive polyarticular juvenile idiopathic arthritis14.Optimizing efficacy to safety ratio of glucocorticoids in rheumatoid arthritis models by leveraging PPARα agonism15.The impact for causal associations between common diseases and inflammatory bowel disease: a disease-wide bidirectional Mendelian randomization study16.Immunomodulatory roles of the HLA family and B2M in atherosclerosis17.Mendelian randomization analysis of the causal relationship between allergic rhinitis and depression and underlying mediation mechanisms18.DNA hypo-methylation of the TNFΑ gene predicts response to methotrexate in rheumatoid arthritis but not in psoriatic arthritis19.Shared Genetic Basis of Autoimmune Diseases and Follicular Lymphoma by Mendelian Randomization and Multi-Omics20.TLPT Rheumatology for Clinicians: Pathogenetic Axes, Master‑Switch Nodes, Minimal and Transversal Attractors, and Bio‑Pharmacology
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