Latest Research in Computational Drug Discovery Methods

10 research papers · 2026 median publication year

Top Research Topics in Computational Drug Discovery Methods

Highest-Cited Papers

  1. Public Database Leakage Distorts Model Rankings in Real-Spectra NMR Structure Elucidation
  2. CDGA: A Host-Based Alignment and Descriptor Analysis Tool for Cyclodextrin Inclusion Complexes
  3. Backbone and side chain 1H, 13C and 15N chemical shift assignment of the cargo-recognition domain MOTH of human TANGO1
  4. AET5: A transcriptome-guided molecular generation framework with contrastive self-supervised learning
  5. Leveraging Discrete Function Decomposability for Scientific Design
  6. CatESO: Differentiable Enzyme Sequence Optimization Guided by Substrate-Aware K cat Prediction
  7. Risk-Sensitive Reward Composition for Conditional GFlowNets
  8. Acep$K_{\rm a}$: Thermodynamics-Informed p$K_{\rm a}$ Prediction and Protonation-State Generation in PlayMolecule AI
  9. Large Discovery Models: Empirically-grounded Model-Based Open-Ended Search
  10. DASH: A Pocket-Aware and Objective-Aware Framework for Million-Scale Structure-Based Molecular Generation
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L3 Region - - 2026 Sep Q3
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