Latest Research in Computational Drug Discovery Methods

13 research papers · 2026 median publication year

Top Research Topics in Computational Drug Discovery Methods

Highest-Cited Papers

  1. Exploring Anti-Breast Cancer Potential and Mechanism of Novel Xanthohumol-Metformin Conjugate by Integrating Network Pharmacology, Molecular Docking and Simulation Approaches
  2. Implementation of Nano Flow Chromatography Coupled to Mass Spectrometry as a Reliable and Sensitive Discovery Lipidomics Platform
  3. Pterin-6-carboxylic Acid Induces Oxidative Stress-Mediated Cytotoxicity, Genotoxicity, and Chromosomal Instability in Mammalian Cells
  4. AI Accelerated Chemical Screening Integrates ChemBERTa to Identify Repositionable CASP4 Inhibitors via MD Simulations and MM/PBSA Analysis
  5. Time-of-flight secondary ion mass spectrometry reference spectra of cholesterol in positive and negative polarity
  6. In vivo acute oral tolerability and antitumor activity of the novel small molecule YB-1 modulator AIGM-2024–4 in a DMBA- induced rat mammary tumor model
  7. Multi-ligand simultaneous docking of Carica papaya leaf phytochemicals, Carpaine and Rutin, reveals multi-mechanism inhibition of cancer proteins BCL-2 and WWP1
  8. Cytotoxic, Drug-Interaction, and Apoptosis-Associated Effects of β-Boswellic Acid and Doxorubicin in Murine 4T1 TNBC-like Cells
  9. BioEMMA: Automated Generation of Model-Specific Escher-Compatible Maps from KEGG Pathways
  10. Evaluation of Camptothecin Through Computational and Experimental Approaches Targeting Membrane Receptors on Breast Cancer Cells for Potential Therapeutic Applications
  11. Computational Screening of Anticancer Phytochemicals From IMPPAT2.0 Database: Molecular Docking and Molecular Dynamics Evaluation Against EGFR and FGFR3
  12. Predicting Quantifiability from Primary Screens to Prioritize Dose-Response Profiling
  13. Novel Phenanthraquinone Derivative from Antarctic Lichen Umbilicaria antarctica Exhibits Apoptotic Activity in Triple-Negative Breast Cancer
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L3 Region - - 2026 Sep Q3

Computational Drug Discovery Methods

13 papers

Top Topics (10)

Computational Drug Discovery Methods2
Hops Chemistry and Applications1
Metabolomics and Mass Spectrometry Studies1
Genomics, phytochemicals, and oxidative stress1
Ion-surface interactions and analysis1
interferon and immune responses1
Biomolecules1
Pharmacological Effects of Medicinal Plants1
Microbial Metabolic Engineering and Bioproduction1
Cancer therapeutics and mechanisms1

Top Publications (13)

1.Exploring Anti-Breast Cancer Potential and Mechanism of Novel Xanthohumol-Metformin Conjugate by Integrating Network Pharmacology, Molecular Docking and Simulation Approaches2.Implementation of Nano Flow Chromatography Coupled to Mass Spectrometry as a Reliable and Sensitive Discovery Lipidomics Platform3.Pterin-6-carboxylic Acid Induces Oxidative Stress-Mediated Cytotoxicity, Genotoxicity, and Chromosomal Instability in Mammalian Cells4.AI Accelerated Chemical Screening Integrates ChemBERTa to Identify Repositionable CASP4 Inhibitors via MD Simulations and MM/PBSA Analysis5.Time-of-flight secondary ion mass spectrometry reference spectra of cholesterol in positive and negative polarity6.In vivo acute oral tolerability and antitumor activity of the novel small molecule YB-1 modulator AIGM-2024–4 in a DMBA- induced rat mammary tumor model7.Multi-ligand simultaneous docking of Carica papaya leaf phytochemicals, Carpaine and Rutin, reveals multi-mechanism inhibition of cancer proteins BCL-2 and WWP18.Cytotoxic, Drug-Interaction, and Apoptosis-Associated Effects of β-Boswellic Acid and Doxorubicin in Murine 4T1 TNBC-like Cells9.BioEMMA: Automated Generation of Model-Specific Escher-Compatible Maps from KEGG Pathways10.Evaluation of Camptothecin Through Computational and Experimental Approaches Targeting Membrane Receptors on Breast Cancer Cells for Potential Therapeutic Applications11.Computational Screening of Anticancer Phytochemicals From IMPPAT2.0 Database: Molecular Docking and Molecular Dynamics Evaluation Against EGFR and FGFR312.Predicting Quantifiability from Primary Screens to Prioritize Dose-Response Profiling13.Novel Phenanthraquinone Derivative from Antarctic Lichen Umbilicaria antarctica Exhibits Apoptotic Activity in Triple-Negative Breast Cancer
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