Latest Research in Mitochondrial Function and Pathology

59 research papers · 2026 median publication year

Top Research Topics in Mitochondrial Function and Pathology

Highest-Cited Papers

  1. ROS-responsive mitochondria-targeting nanocomposite reprograms the IRGM1–mitophagy axis to restore mitochondrial homeostasis and suppress pyroptosis in intervertebral disc degeneration
  2. The mechanism by which transcription factors regulate ferroptosis in diabetic complications and its therapeutic potential
  3. Cholesterol maintains the degradative capacity of lysosomes during clearance and recycling of dysfunctional mitochondria
  4. Click chemistry-modified cardiomyocytes enhance cardiac contractility and prevent remodeling in ischemia-reperfusion injured hearts
  5. Targeting ferroptosis alleviates burn-induced acute kidney injury
  6. Trigeminal and facial branchiomotor neurons have shared muscle targets in zebrafish larvae
  7. Saquinavir inhibits pyroptosis by regulating NLRP3 degradation to alleviate acute lung injury
  8. MAFLD enhances BMP-2-induced heterotopic ossification via the LRP6/Wnt/β-catenin axis
  9. Direct activation of SARM1 by dsDNA is not supported by biochemical and cellular evidence
  10. STING Aggravates Ferroptosis in Septic Acute Kidney Injury by Promoting Ubiquitin–Proteasome–Dependent Degradation of FSP1
  11. Nerve injury-induced protein 2 preserves lysosomal membrane integrity to suppress ferroptosis
  12. Astragalus polysaccharides alleviate burn sepsis induced lung injury by suppressing the WTAP/m⁶A/PFKFB3 axis to reduce endothelial pyroptosis
  13. Endoplasmic reticulum stress-mediated PPARα-DDX3X interaction promotes immune-induced liver injury
  14. Human testis-specific TTRP regulates circadian clock as an evolutionarily young natural antisense transcript of PER2
  15. Umbilical Moxibustion Enhances Pirfenidone-Mediated Attenuation of Idiopathic Pulmonary Fibrosis by Inhibiting the ZBP1-PANoptosis Pathway
  16. Pharmacological activation of SIRT1 alleviates sepsis-associated acute kidney injury by improving renal mitochondrial energy metabolism
  17. The Development of Cellular Aging Models Based on AD-MSCs
  18. SIRT3-dependent mitochondrial redox homeostasis protects against age-related tendon degeneration
  19. Bag-1 modulates lung ischemia-reperfusion injury by regulating BCL-2 family proteins and IP3R-mediated calcium release
  20. Selective EP4 Receptor Antagonism for Osteoarthritis Pain: Emerging Evidence and Future Directions for KF-0210
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L3 Region - - 2026 Sep Q3

Mitochondrial Function and Pathology

59 papers

Top Topics (10)

Ferroptosis and cancer prognosis10
Inflammasome and immune disorders5
Mitochondrial Function and Pathology4
Extracellular vesicles in disease4
Sirtuins and Resveratrol in Medicine3
Autophagy in Disease and Therapy2
Cardiac Fibrosis and Remodeling2
Endoplasmic Reticulum Stress and Disease2
Muscle Physiology and Disorders2
Spine and Intervertebral Disc Pathology1

Top Publications (20)

1.ROS-responsive mitochondria-targeting nanocomposite reprograms the IRGM1–mitophagy axis to restore mitochondrial homeostasis and suppress pyroptosis in intervertebral disc degeneration2.The mechanism by which transcription factors regulate ferroptosis in diabetic complications and its therapeutic potential3.Cholesterol maintains the degradative capacity of lysosomes during clearance and recycling of dysfunctional mitochondria4.Click chemistry-modified cardiomyocytes enhance cardiac contractility and prevent remodeling in ischemia-reperfusion injured hearts5.Targeting ferroptosis alleviates burn-induced acute kidney injury6.Trigeminal and facial branchiomotor neurons have shared muscle targets in zebrafish larvae7.Saquinavir inhibits pyroptosis by regulating NLRP3 degradation to alleviate acute lung injury8.MAFLD enhances BMP-2-induced heterotopic ossification via the LRP6/Wnt/β-catenin axis9.Direct activation of SARM1 by dsDNA is not supported by biochemical and cellular evidence10.STING Aggravates Ferroptosis in Septic Acute Kidney Injury by Promoting Ubiquitin–Proteasome–Dependent Degradation of FSP111.Nerve injury-induced protein 2 preserves lysosomal membrane integrity to suppress ferroptosis12.Astragalus polysaccharides alleviate burn sepsis induced lung injury by suppressing the WTAP/m⁶A/PFKFB3 axis to reduce endothelial pyroptosis13.Endoplasmic reticulum stress-mediated PPARα-DDX3X interaction promotes immune-induced liver injury14.Human testis-specific TTRP regulates circadian clock as an evolutionarily young natural antisense transcript of PER215.Umbilical Moxibustion Enhances Pirfenidone-Mediated Attenuation of Idiopathic Pulmonary Fibrosis by Inhibiting the ZBP1-PANoptosis Pathway16.Pharmacological activation of SIRT1 alleviates sepsis-associated acute kidney injury by improving renal mitochondrial energy metabolism17.The Development of Cellular Aging Models Based on AD-MSCs18.SIRT3-dependent mitochondrial redox homeostasis protects against age-related tendon degeneration19.Bag-1 modulates lung ischemia-reperfusion injury by regulating BCL-2 family proteins and IP3R-mediated calcium release20.Selective EP4 Receptor Antagonism for Osteoarthritis Pain: Emerging Evidence and Future Directions for KF-0210
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