Latest Research in Single-cell and spatial transcriptomics

34 research papers · 2026 median publication year

Top Research Topics in Single-cell and spatial transcriptomics

Highest-Cited Papers

  1. Multidimensional analysis on the potential of cell cycle-related gene STMN1 as a tumor biomarker
  2. CGP60474, a novel MITD1-targeted inhibitor for bladder cancer progression via CDK4/cyclin D1 pathway modulation
  3. Beyond Tumor-Intrinsic STAT3: Integrating Metabolic and Immune Communication in the Tumor Microenvironment of Cervical, Ovarian, and Endometrial Cancers
  4. Targeting endothelial CYP3A5 in lung adenocarcinoma remodels the immunosuppressive microenvironment via VEGF inhibition: Mechanistic insights from Diosmetin
  5. PTK6 inhibition by tilfrinib hinders the proliferation and migration of ovarian cancer cells
  6. p16INK4a and DNA methylation clocks in women treated with chemotherapy for early breast cancer
  7. Identification of molecular subtypes and prognostic models for head and neck squamous cell carcinomas based on PFKFB4
  8. Subtype-Specific Prognostic and Molecular Significance of ADGRD1 in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma
  9. Pro-inflammatory and autophagic pathways in lung cancer: dysregulation of key genes ADINR, C/EBPα, CHAST, ATG5, IL-1B, and DICER1-AS1
  10. FABP4 characterizes metabolic–immune interactions and serves as a prognostic biomarker across gynecologic malignancies: a multi-omics integrative analysis
  11. Integrated single-cell and bulk transcriptomic analysis reveals an epithelial cell-derived prognostic and immunotherapeutic signature with ADAM12 as a key functional regulator in non-small cell lung cancer
  12. The MAZ-POLD1 Signaling Axis Drives Cisplatin Resistance in Bladder Cancer by Activating DNA Damage Repair
  13. Identification of STAT1 as a biomarker for lymph node metastasis in esophageal squamous cell carcinoma
  14. Amplification-Driven S100A11 Overexpression in Hepatocellular Carcinoma Is Associated with Metabolic Reprogramming, ECM Remodelling, and Immune Evasion: A Pan-Cancer Genomic Study
  15. Detection of a mosaic DNMT3A variant with potential neurodevelopmental and malignancy risks in monozygotic twins: a case report
  16. Genotype‐Informed Whole‐Animal Kinome Screening Reveals Shared Kinase Vulnerabilities Across Driver Contexts in PDAC
  17. Dissecting the myeloid cell-driven ecosystems through multi-omics and heterogeneous graph learning in pancreatic ductal adenocarcinoma
  18. Identification of JAML as an Immune-Associated Prognostic Marker in Non-Small Cell Lung Cancer
  19. Immunity-Related Gene Characterization and Targeted Therapy in Lung Cancer: A Data Mining Approach to Predicting Immunotherapy Response
  20. MYSM1 suppresses cervical cancer progression by triggering ITPR1-mediated autophagy
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L3 Region - - 2026 Sep Q3

Single-cell and spatial transcriptomics

34 papers

Top Topics (10)

Single-cell and spatial transcriptomics4
Esophageal Cancer Research and Treatment3
Cancer Immunotherapy and Biomarkers3
Cytokine Signaling Pathways and Interactions2
Bladder and Urothelial Cancer Treatments2
Ferroptosis and cancer prognosis2
Cancer Cells and Metastasis2
Neuroblastoma Research and Treatments1
Protein Degradation and Inhibitors1
Cancer, Stress, Anesthesia, and Immune Response1

Top Publications (20)

1.Multidimensional analysis on the potential of cell cycle-related gene STMN1 as a tumor biomarker2.CGP60474, a novel MITD1-targeted inhibitor for bladder cancer progression via CDK4/cyclin D1 pathway modulation3.Beyond Tumor-Intrinsic STAT3: Integrating Metabolic and Immune Communication in the Tumor Microenvironment of Cervical, Ovarian, and Endometrial Cancers4.Targeting endothelial CYP3A5 in lung adenocarcinoma remodels the immunosuppressive microenvironment via VEGF inhibition: Mechanistic insights from Diosmetin5.PTK6 inhibition by tilfrinib hinders the proliferation and migration of ovarian cancer cells6.p16INK4a and DNA methylation clocks in women treated with chemotherapy for early breast cancer7.Identification of molecular subtypes and prognostic models for head and neck squamous cell carcinomas based on PFKFB48.Subtype-Specific Prognostic and Molecular Significance of ADGRD1 in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma9.Pro-inflammatory and autophagic pathways in lung cancer: dysregulation of key genes ADINR, C/EBPα, CHAST, ATG5, IL-1B, and DICER1-AS110.FABP4 characterizes metabolic–immune interactions and serves as a prognostic biomarker across gynecologic malignancies: a multi-omics integrative analysis11.Integrated single-cell and bulk transcriptomic analysis reveals an epithelial cell-derived prognostic and immunotherapeutic signature with ADAM12 as a key functional regulator in non-small cell lung cancer12.The MAZ-POLD1 Signaling Axis Drives Cisplatin Resistance in Bladder Cancer by Activating DNA Damage Repair13.Identification of STAT1 as a biomarker for lymph node metastasis in esophageal squamous cell carcinoma14.Amplification-Driven S100A11 Overexpression in Hepatocellular Carcinoma Is Associated with Metabolic Reprogramming, ECM Remodelling, and Immune Evasion: A Pan-Cancer Genomic Study15.Detection of a mosaic DNMT3A variant with potential neurodevelopmental and malignancy risks in monozygotic twins: a case report16.Genotype‐Informed Whole‐Animal Kinome Screening Reveals Shared Kinase Vulnerabilities Across Driver Contexts in PDAC17.Dissecting the myeloid cell-driven ecosystems through multi-omics and heterogeneous graph learning in pancreatic ductal adenocarcinoma18.Identification of JAML as an Immune-Associated Prognostic Marker in Non-Small Cell Lung Cancer19.Immunity-Related Gene Characterization and Targeted Therapy in Lung Cancer: A Data Mining Approach to Predicting Immunotherapy Response20.MYSM1 suppresses cervical cancer progression by triggering ITPR1-mediated autophagy
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