Latest Research in Epigenetics and DNA Methylation

15 research papers · 2026 median publication year

Top Research Topics in Epigenetics and DNA Methylation

Highest-Cited Papers

  1. HAUS6 serves as a potential prognostic and immunotherapy biomarker in hepatocellular carcinoma
  2. MRC1⁺ macrophages and endothelial PTPRM signalling characterize a microvascular invasion–associated tumor ecosystem in hepatocellular carcinoma
  3. FANCB as a prognostic biomarker and therapeutic target in hepatocellular carcinoma with insights from pan-cancer analysis and experimental validation
  4. PRMT1-Mediated Arginine Methylation Redirects SMAD4 Signaling to Promote Metastasis in Pancreatic Cancer
  5. Protein-residual ECM N-glycosylation delineates a composition-resolved myCAF-enriched stromal state in pancreatic ductal adenocarcinoma
  6. RNF113A Promotes Colorectal Cancer Metastasis by Regulating TGF-β Pathway and EMT via Ubiquitin-Mediated Degradation of SNIP1
  7. Mechanisms of Immune Cell Dysregulation in Pancreatic Ductal Adenocarcinoma
  8. MCM10, regulated by METTL3/ YTHDF1-mediated m6A modification, contributes to colorectal cancer progression through induction of M2 macrophage polarization
  9. The epigenetic regulator ALKBH5 facilitates the early adaptation of hepatocellular carcinoma cells to sorafenib treatment
  10. Targeting CTGF + cancer-associated fibroblasts disrupts tumor–stroma crosstalk in pancreatic ductal adenocarcinoma
  11. DNMT1 is associated with QDPR downregulation and chemotherapy response in lung adenocarcinoma
  12. The GSEC-encoded polypeptide GESP drives colorectal cancer tumorigenesis via NPM1-c-Myc-mediated repression of NDRG1
  13. Supermeres containing Discoidin Domain Receptor 1 extracellular domain promote collagen alignment and immune exclusion in microsatellite stable colorectal cancer
  14. Expression and functional analysis of TIMM44 in cervical cancer
  15. KRAS and SKIL mutations synergistically promote pancreatic tumorigenesis through the ubiquitin-proteasome-mediated degradation of Smad4
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L3 Region - - 2026 Sep Q3

Epigenetics and DNA Methylation

15 papers

Top Topics (10)

Epigenetics and DNA Methylation2
Ferroptosis and cancer prognosis1
Single-cell and spatial transcriptomics1
Hepatocellular Carcinoma Treatment and Prognosis1
Cancer-related gene regulation1
Advanced Proteomics Techniques and Applications1
Ubiquitin and proteasome pathways1
Pancreatic and Hepatic Oncology Research1
RNA modifications and cancer1
Connective Tissue Growth Factor Research1

Top Publications (15)

1.HAUS6 serves as a potential prognostic and immunotherapy biomarker in hepatocellular carcinoma2.MRC1⁺ macrophages and endothelial PTPRM signalling characterize a microvascular invasion–associated tumor ecosystem in hepatocellular carcinoma3.FANCB as a prognostic biomarker and therapeutic target in hepatocellular carcinoma with insights from pan-cancer analysis and experimental validation4.PRMT1-Mediated Arginine Methylation Redirects SMAD4 Signaling to Promote Metastasis in Pancreatic Cancer5.Protein-residual ECM N-glycosylation delineates a composition-resolved myCAF-enriched stromal state in pancreatic ductal adenocarcinoma6.RNF113A Promotes Colorectal Cancer Metastasis by Regulating TGF-β Pathway and EMT via Ubiquitin-Mediated Degradation of SNIP17.Mechanisms of Immune Cell Dysregulation in Pancreatic Ductal Adenocarcinoma8.MCM10, regulated by METTL3/ YTHDF1-mediated m6A modification, contributes to colorectal cancer progression through induction of M2 macrophage polarization9.The epigenetic regulator ALKBH5 facilitates the early adaptation of hepatocellular carcinoma cells to sorafenib treatment10.Targeting CTGF + cancer-associated fibroblasts disrupts tumor–stroma crosstalk in pancreatic ductal adenocarcinoma11.DNMT1 is associated with QDPR downregulation and chemotherapy response in lung adenocarcinoma12.The GSEC-encoded polypeptide GESP drives colorectal cancer tumorigenesis via NPM1-c-Myc-mediated repression of NDRG113.Supermeres containing Discoidin Domain Receptor 1 extracellular domain promote collagen alignment and immune exclusion in microsatellite stable colorectal cancer14.Expression and functional analysis of TIMM44 in cervical cancer15.KRAS and SKIL mutations synergistically promote pancreatic tumorigenesis through the ubiquitin-proteasome-mediated degradation of Smad4
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